Vegas will play a coach driver and Gibson a tour guide in Murder On The Blackpool Express.
Vegas, 46, plays a coach driver and Gibson, 40, a tour guide in Murder On The Blackpool Express, a comedy take on Agatha Christie-style murder mysteries.
Nigel Havers, Una Stubbs and Griff Rhys Jones will also appear in the drama, which is being shot in location in Blackpool and will air on Gold.
Comedian Vegas said: “If the script read-through is anything to go by, this is not only going to be immense fun to film, but a real treat for comedy lovers and whodunnits alike.
Gibson, who shot to fame in Peter Kay’s Car Share, said: “I’m so excited to be involved in a murder mystery! The script is very funny and it’s such a pleasure to be working with Johnny and such a wonderful cast.”
Directed by Simon Delaney, whose credits include Cold Feet, Stella and Lead Balloon, Murder On The Blackpool Express will air on Gold later this year.