Felix Jones, Donncha O'Callaghan, James Coughlan, Stephen Archer and Mike Sherry have all been released from the Ireland camp but Jones is the only one of the quintet to start in the Rabo Pro 12 clash.
Munster head coach Rob Penney has made five changes to the team that beat the Ospreys in the province's last outing at Thomond Park.
David Kilcoyne drops to the replacements bench, with James Cronin coming into the front row alongside BJ Botha and hooker Damien Varley who skippers the side.
Billy Holland returns in the second row ahead of Donncha O'Callaghan to form a partnership with David Foley.
There are three changes in the backs division with Cathal Sheridan coming in for Duncan Williams at scrum half and JJ Hanrahan will earn his 20th cap for Munster as he replaces the injured Ian Keatley at out-half.
MUNSTER team to face the Cardiff Blues: (15-9) Felix Jones; Andrew Conway, Casey Laulala, Ivan Dineen, Johne Murphy; JJ Hanrahan, Cathal Sheridan; (1-9) James Cronin, Damien Varley (capt), BJ Botha, David Foley, Billy Holland, David O'Callaghan, Sean Dougall, CJ Stander.
Replacements: (16-23) Mike Sherry, David Kilcoyne, Stephen Archer, Donncha O'Callaghan, James Coughlan, Duncan Williams, Johnny Holland, Denis Hurley.